Starting a tumor off wrong
نویسندگان
چکیده
منابع مشابه
Starting a tumor off wrong
A neuploidy is a hallmark of cancer, but the path from mutation to extra chromosomes is unclear. Now, Caldwell et al. help fi ll this gap, showing that a cancer-causing mutation promotes chromosome doubling by unfastening the mitotic spindle and hindering cell division. The genome of a cancer cell is a mess, with breaks, rearrangements, and super-fl uous chromosomes. Many researchers speculate ...
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Chronic inflammation drives initiation and progression of many malignancies, including pancreatic cancer. In this issue, Liou et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201301001) report that inflammatory macrophages are major players in the earliest stages of pancreatic cancer. They show that paracrine signals from the macrophages activate the nuclear factor κB transcriptional p...
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In setting up a formal system to specify a grammar formalism, the conventional (mathematical) wisdom is to start with primitives (basic primitive structures) as simple as possible and then to introduce various operations for constructing more complex structures. An alternate approach is to start with more complex primitives, which directly capture some crucial linguistic properties and then to ...
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In setting up a formal system to specify a grammar formalism, the conventional (mathematical) wisdom is to start with primitives (basic primitive structures) as simple as possible, and then introduce various operations for constructing more complex structures. An alternate approach is to start with complex (more complicated) primitives, which directly capture some crucial linguistic properties ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1787iti1